VWFA and cache domain-containing protein 1 (CACHD1)
Homo sapiens — UniProt Q5VU97
Data last refreshed: (UniProt release unknown)
Key facts
VWFA and cache domain-containing protein 1 (CACHD1) is a protein from Homo sapiens identified by UniProt accession Q5VU97, 1274 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q5VU97; gene symbol CACHD1.
- Organism: Homo sapiens.
- Length: 1274 amino acids.
- Top disease associations (Open Targets): Meniere disease, peak expiratory flow and worry measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | VWFA and cache domain-containing protein 1 |
|---|---|
| UniProt accession | Q5VU97 |
| Gene | CACHD1 |
| Organism | Homo sapiens |
| Length | 1274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- Meniere disease · score 0.32
- peak expiratory flow · score 0.31
- worry measurement · score 0.30
- genetic disorder · score 0.19
- joint disease · score 0.16
- metabolite measurement · score 0.07
- deafness · score 0.07
- hearing loss, autosomal dominant 75 · score 0.05
- hearing loss, autosomal dominant 77 · score 0.05
- X-linked hereditary sensory and autonomic neuropathy with hearing loss · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VU97-F1 | alphafold | PREDICTED | 77.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VU97.
Amino-acid sequence (1274 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CACHD1?
The strongest Open Targets associations for CACHD1 are Meniere disease, peak expiratory flow, worry measurement, genetic disorder and joint disease.
How long is the CACHD1 protein?
The Homo sapiens CACHD1 protein (UniProt Q5VU97) is 1274 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VU97 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VU97 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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