Uncharacterized protein C1orf53 (C1orf53)
Homo sapiens — UniProt Q5VUE5
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C1orf53 (C1orf53) is a protein from Homo sapiens identified by UniProt accession Q5VUE5, 145 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q5VUE5; gene symbol C1orf53.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, eosinophil count and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C1orf53 |
|---|---|
| UniProt accession | Q5VUE5 |
| Gene | C1orf53 |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.26
- eosinophil count · score 0.26
- self reported educational attainment · score 0.25
- neurodegenerative disease · score 0.23
- creatinine clearance measurement · score 0.21
- sex hormone-binding globulin measurement · score 0.16
- protein measurement · score 0.14
- breast milk measurement · score 0.12
- sleep measurement · score 0.09
- smoking status measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VUE5-F1 | alphafold | PREDICTED | 73.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VUE5.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf53?
The strongest Open Targets associations for C1orf53 are heel bone mineral density, eosinophil count, self reported educational attainment, neurodegenerative disease and creatinine clearance measurement.
How long is the C1orf53 protein?
The Homo sapiens C1orf53 protein (UniProt Q5VUE5) is 145 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VUE5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VUE5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.