Arylacetamide deacetylase-like 3 (AADACL3)
Homo sapiens — UniProt Q5VUY0
Data last refreshed: (UniProt release unknown)
Key facts
Arylacetamide deacetylase-like 3 (AADACL3) is a protein from Homo sapiens identified by UniProt accession Q5VUY0, 407 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q5VUY0; gene symbol AADACL3.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): breast carcinoma, psoriasis and Down syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arylacetamide deacetylase-like 3 |
|---|---|
| UniProt accession | Q5VUY0 |
| Gene | AADACL3 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.04
- psoriasis · score 0.03
- Down syndrome · score 0.02
- Parkinson disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VUY0-F1 | alphafold | PREDICTED | 94.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VUY0.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AADACL3?
The strongest Open Targets associations for AADACL3 are breast carcinoma, psoriasis, Down syndrome and Parkinson disease.
How long is the AADACL3 protein?
The Homo sapiens AADACL3 protein (UniProt Q5VUY0) is 407 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VUY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VUY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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