Arylacetamide deacetylase-like 4 (AADACL4)
Homo sapiens — UniProt Q5VUY2
Data last refreshed: (UniProt release unknown)
Key facts
Arylacetamide deacetylase-like 4 (AADACL4) is a protein from Homo sapiens identified by UniProt accession Q5VUY2, 407 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q5VUY2; gene symbol AADACL4.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cup-to-disc ratio measurement and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arylacetamide deacetylase-like 4 |
|---|---|
| UniProt accession | Q5VUY2 |
| Gene | AADACL4 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- cup-to-disc ratio measurement · score 0.06
- sitting height measurement · score 0.05
- optic cup area measurement · score 0.03
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- psoriasis · score 0.01
- uterine sarcoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VUY2-F1 | alphafold | PREDICTED | 96.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VUY2.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AADACL4?
The strongest Open Targets associations for AADACL4 are neurodegenerative disease, cup-to-disc ratio measurement, sitting height measurement, optic cup area measurement and carcinoma of liver and intrahepatic biliary tract.
How long is the AADACL4 protein?
The Homo sapiens AADACL4 protein (UniProt Q5VUY2) is 407 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VUY2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VUY2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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