OTU domain-containing protein 1 (OTUD1)
Homo sapiens — UniProt Q5VV17
Data last refreshed: (UniProt release unknown)
Key facts
OTU domain-containing protein 1 (OTUD1) is a protein from Homo sapiens identified by UniProt accession Q5VV17, 481 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q5VV17; gene symbol OTUD1.
- Organism: Homo sapiens.
- Length: 481 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | OTU domain-containing protein 1 |
|---|---|
| UniProt accession | Q5VV17 |
| Gene | OTUD1 |
| Organism | Homo sapiens |
| Length | 481 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- body height · score 0.41
- mean corpuscular volume · score 0.37
- high density lipoprotein cholesterol measurement · score 0.29
- sitting height measurement · score 0.27
- protein measurement · score 0.25
- cystatin C measurement · score 0.23
- non-small cell lung carcinoma · score 0.10
- cancer · score 0.09
- creatinine measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VV17-F1 | alphafold | PREDICTED | 60.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VV17.
Amino-acid sequence (481 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTUD1?
The strongest Open Targets associations for OTUD1 are neurodegenerative disease, body height, mean corpuscular volume, high density lipoprotein cholesterol measurement and sitting height measurement.
How long is the OTUD1 protein?
The Homo sapiens OTUD1 protein (UniProt Q5VV17) is 481 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VV17 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VV17 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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