Dyslexia-associated protein KIAA0319 (KIAA0319)
Homo sapiens — UniProt Q5VV43
Data last refreshed: (UniProt release unknown)
Key facts
Dyslexia-associated protein KIAA0319 (KIAA0319) is a protein from Homo sapiens identified by UniProt accession Q5VV43, 1072 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q5VV43; gene symbol KIAA0319.
- Organism: Homo sapiens.
- Length: 1072 amino acids.
- Top disease associations (Open Targets): dyslexia, alkaline phosphatase measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dyslexia-associated protein KIAA0319 |
|---|---|
| UniProt accession | Q5VV43 |
| Gene | KIAA0319 |
| Organism | Homo sapiens |
| Length | 1072 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- dyslexia · score 0.39
- alkaline phosphatase measurement · score 0.36
- body height · score 0.27
- glioblastoma multiforme · score 0.24
- lung adenocarcinoma · score 0.18
- Blackfan-Diamond anemia · score 0.08
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- testosterone measurement · score 0.06
- hemolytic anemia due to adenylate kinase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VV43-F1 | alphafold | PREDICTED | 70.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VV43.
Amino-acid sequence (1072 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KIAA0319?
The strongest Open Targets associations for KIAA0319 are dyslexia, alkaline phosphatase measurement, body height, glioblastoma multiforme and lung adenocarcinoma.
How long is the KIAA0319 protein?
The Homo sapiens KIAA0319 protein (UniProt Q5VV43) is 1072 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VV43 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VV43 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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