Peptidyl-prolyl cis-trans isomerase FKBP1C (FKBP1C)
Homo sapiens — UniProt Q5VVH2
Data last refreshed: (UniProt release unknown)
Key facts
Peptidyl-prolyl cis-trans isomerase FKBP1C (FKBP1C) is a protein from Homo sapiens identified by UniProt accession Q5VVH2, 108 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q5VVH2; gene symbol FKBP1C.
- Organism: Homo sapiens.
- Length: 108 amino acids.
- Top disease associations (Open Targets): DNA methylation, age at first birth measurement and hypertrophic cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase FKBP1C |
|---|---|
| UniProt accession | Q5VVH2 |
| Gene | FKBP1C |
| Organism | Homo sapiens |
| Length | 108 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- DNA methylation · score 0.27
- age at first birth measurement · score 0.12
- hypertrophic cardiomyopathy · score 0.06
- blood protein measurement · score 0.06
- dilated cardiomyopathy · score 0.06
- left ventricular noncompaction · score 0.05
- Arrhythmogenic right ventricular dysplasia · score 0.05
- Sensorineural deafness with dilated cardiomyopathy · score 0.04
- hypertrophic cardiomyopathy 4 · score 0.04
- hypertrophic cardiomyopathy 15 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VVH2-F1 | alphafold | PREDICTED | 95.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VVH2.
Amino-acid sequence (108 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FKBP1C?
The strongest Open Targets associations for FKBP1C are DNA methylation, age at first birth measurement, hypertrophic cardiomyopathy, blood protein measurement and dilated cardiomyopathy.
How long is the FKBP1C protein?
The Homo sapiens FKBP1C protein (UniProt Q5VVH2) is 108 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VVH2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VVH2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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