Ubiquitin-conjugating enzyme E2 U (UBE2U)
Homo sapiens — UniProt Q5VVX9
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-conjugating enzyme E2 U (UBE2U) is a protein from Homo sapiens identified by UniProt accession Q5VVX9, 321 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q5VVX9; gene symbol UBE2U.
- Organism: Homo sapiens.
- Length: 321 amino acids.
- Top disease associations (Open Targets): bacterial meningitis, blood protein measurement and refractive error measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 U |
|---|---|
| UniProt accession | Q5VVX9 |
| Gene | UBE2U |
| Organism | Homo sapiens |
| Length | 321 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- bacterial meningitis · score 0.31
- blood protein measurement · score 0.30
- refractive error measurement · score 0.25
- brain measurement · score 0.23
- cortical surface area measurement · score 0.19
- cortical thickness · score 0.19
- metabolite measurement · score 0.12
- joint disease · score 0.11
- PHF-tau measurement · score 0.09
- Abnormal sperm morphology · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VVX9-F1 | alphafold | PREDICTED | 70.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VVX9.
Amino-acid sequence (321 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBE2U?
The strongest Open Targets associations for UBE2U are bacterial meningitis, blood protein measurement, refractive error measurement, brain measurement and cortical surface area measurement.
How long is the UBE2U protein?
The Homo sapiens UBE2U protein (UniProt Q5VVX9) is 321 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VVX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VVX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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