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Transcription elongation regulator 1-like protein (TCERG1L)

Homo sapiens — UniProt Q5VWI1

Gene: TCERG1LHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transcription elongation regulator 1-like protein (TCERG1L) is a protein from Homo sapiens identified by UniProt accession Q5VWI1, 586 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

  • UniProt accession: Q5VWI1; gene symbol TCERG1L.
  • Organism: Homo sapiens.
  • Length: 586 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, body mass index and body fat percentage.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTranscription elongation regulator 1-like protein
UniProt accessionQ5VWI1
GeneTCERG1L
OrganismHomo sapiens
Length586 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (53)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.42
  • body mass index · score 0.40
  • body fat percentage · score 0.38
  • self reported educational attainment · score 0.36
  • DNA methylation · score 0.36
  • hearing loss · score 0.33
  • ototoxicity · score 0.33
  • response to cisplatin · score 0.33
  • diffuse plaque measurement · score 0.32
  • protein measurement · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5VWI1-F1alphafoldPREDICTED57.53—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VWI1.

Amino-acid sequence (586 residues)

MQAGARFQRR RRQLQQQQPR RRQPLLWPMD AEPPPPPPWV WMVPGSAGLL RLSAGVVVPP VLLASAPPPA APLLPGLPGW PAPSEPVLPL LPLPSAPDSA AAAAAHPFPA LHGQWLFGGH SPSLGLPPSS TVELVPVFPH LCPSALATPI GKSWIDKRIP NCKIFFNNSF ALDSTWIHPE ESRFFHGHEK PRLLANQVAV SLSRPAPASR PLPTVVLAPQ PIPGGCHNSL KVTSSPAIAI ATAAAAAMVS VDPENLRGPS PSSVQPRHFL TLAPIKIPLR TSPVSDTRTE RGRVARPPAL MLRAQKSRDG DKEDKEPPPM LGGGEDSTAR GNRPVASTPV PGSPWCVVWT GDDRVFFFNP TMHLSVWEKP MDLKDRGDLN RIIEDPPHKR KLEAPATDNS DGSSSEDNRE DQDVKTKRNR TEGCGSPKPE EAKREDKGTR TPPPQILLPL EERVTHFRDM LLERGVSAFS TWEKELHKIV FDPRYLLLNS EERKQIFEQF VKTRIKEEYK EKKSKLLLAK EEFKKLLEES KVSPRTTFKE FAEKYGRDQR FRLVQKRKDQ EHFFNQFILI LKKRDKENRL RLRKMR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TCERG1L?

The strongest Open Targets associations for TCERG1L are neurodegenerative disease, body mass index, body fat percentage, self reported educational attainment and DNA methylation.

How long is the TCERG1L protein?

The Homo sapiens TCERG1L protein (UniProt Q5VWI1) is 586 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5VWI1
GeneTCERG1L
OrganismHomo sapiens
Length586
Binders0
Diseases53
View on UniProt