FYN-binding protein 2 (FYB2)
Homo sapiens — UniProt Q5VWT5
Data last refreshed: (UniProt release unknown)
Key facts
FYN-binding protein 2 (FYB2) is a protein from Homo sapiens identified by UniProt accession Q5VWT5, 728 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q5VWT5; gene symbol FYB2.
- Organism: Homo sapiens.
- Length: 728 amino acids.
- Top disease associations (Open Targets): adolescent idiopathic scoliosis, Visual loss and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FYN-binding protein 2 |
|---|---|
| UniProt accession | Q5VWT5 |
| Gene | FYB2 |
| Organism | Homo sapiens |
| Length | 728 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.32
- Visual loss · score 0.16
- glomerular filtration rate · score 0.11
- blood protein measurement · score 0.10
- platelet count · score 0.07
- lymphocyte percentage of leukocytes · score 0.05
- body height · score 0.05
- reticulocyte count · score 0.04
- breast carcinoma · score 0.04
- low density lipoprotein cholesterol measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VWT5-F1 | alphafold | PREDICTED | 53.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VWT5.
Amino-acid sequence (728 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FYB2?
The strongest Open Targets associations for FYB2 are adolescent idiopathic scoliosis, Visual loss, glomerular filtration rate, blood protein measurement and platelet count.
How long is the FYB2 protein?
The Homo sapiens FYB2 protein (UniProt Q5VWT5) is 728 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VWT5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VWT5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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