KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2)
Homo sapiens — UniProt Q5VWX1
Data last refreshed: (UniProt release unknown)
Key facts
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2) is a protein from Homo sapiens identified by UniProt accession Q5VWX1, 349 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q5VWX1; gene symbol KHDRBS2.
- Organism: Homo sapiens.
- Length: 349 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, protein measurement and peak expiratory flow.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | KH domain-containing, RNA-binding, signal transduction-associated protein 2 |
|---|---|
| UniProt accession | Q5VWX1 |
| Gene | KHDRBS2 |
| Organism | Homo sapiens |
| Length | 349 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.37
- protein measurement · score 0.34
- peak expiratory flow · score 0.33
- mean corpuscular volume · score 0.33
- mean corpuscular hemoglobin concentration · score 0.32
- mathematical ability · score 0.32
- esophageal adenocarcinoma · score 0.31
- chronotype measurement · score 0.28
- sunburn · score 0.27
- erythrocyte count · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VWX1-F1 | alphafold | PREDICTED | 69.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VWX1.
Amino-acid sequence (349 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KHDRBS2?
The strongest Open Targets associations for KHDRBS2 are FEV/FVC ratio, protein measurement, peak expiratory flow, mean corpuscular volume and mean corpuscular hemoglobin concentration.
How long is the KHDRBS2 protein?
The Homo sapiens KHDRBS2 protein (UniProt Q5VWX1) is 349 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VWX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VWX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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