Sushi domain-containing protein 4 (SUSD4)

About Sushi domain-containing protein 4

Sushi domain-containing protein 4 (SUSD4) is a protein from Homo sapiens identified by UniProt accession Q5VX71, 490 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Sushi domain-containing protein 4
UniProt accession	Q5VX71
Gene	SUSD4
Organism	Homo sapiens
Length	490 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

excessive daytime sleepiness measurement · score 0.30
PHF-tau measurement · score 0.20
glucuronate measurement · score 0.17
neoplasm · score 0.10
cancer · score 0.08
metabolite measurement · score 0.07
esophageal adenocarcinoma · score 0.03
Huntington disease · score 0.03
leukoencephalopathy, diffuse hereditary, with spheroids 1 · score 0.03
Hereditary diffuse leukoencephalopathy with axonal spheroids and pigmented glia · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VX71-F1	alphafold	PREDICTED	70.86	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VX71.

Amino-acid sequence (490 residues)

MYHGMNPSNG DGFLEQQQQQ QQPQSPQRLL AVILWFQLAL CFGPAQLTGG FDDLQVCADP GIPENGFRTP SGGVFFEGSV ARFHCQDGFK LKGATKRLCL KHFNGTLGWI PSDNSICVQE DCRIPQIEDA EIHNKTYRHG EKLIITCHEG FKIRYPDLHN MVSLCRDDGT WNNLPICQGC LRPLASSNGY VNISELQTSF PVGTVISYRC FPGFKLDGSA YLECLQNLIW SSSPPRCLAL EVCPLPPMVS HGDFVCHPRP CERYNHGTVV EFYCDPGYSL TSDYKYITCQ YGEWFPSYQV YCIKSEQTWP STHETLLTTW KIVAFTATSV LLVLLLVILA RMFQTKFKAH FPPRGPPRSS SSDPDFVVVD GVPVMLPSYD EAVSGGLSAL GPGYMASVGQ GCPLPVDDQS PPAYPGSGDT DTGPGESETC DSVSGSSELL QSLYSPPRCQ ESTHPASDNP DIIASTAEEV ASTSPGIDIA DEIPLMEEDP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards