Lipase member K (LIPK)
Homo sapiens — UniProt Q5VXJ0
Data last refreshed: (UniProt release unknown)
Key facts
Lipase member K (LIPK) is a protein from Homo sapiens identified by UniProt accession Q5VXJ0, 399 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q5VXJ0; gene symbol LIPK.
- Organism: Homo sapiens.
- Length: 399 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, cutaneous melanoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lipase member K |
|---|---|
| UniProt accession | Q5VXJ0 |
| Gene | LIPK |
| Organism | Homo sapiens |
| Length | 399 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.11
- cutaneous melanoma · score 0.11
- squamous cell lung carcinoma · score 0.10
- PHF-tau measurement · score 0.03
- self reported educational attainment · score 0.03
- non-small cell lung carcinoma · score 0.02
- tumor necrosis factor receptor superfamily member 6 measurement · score 0.02
- type 1 diabetes mellitus · score 0.02
- psoriasis · score 0.00
- COVID-19 · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VXJ0-F1 | alphafold | PREDICTED | 92.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VXJ0.
Amino-acid sequence (399 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LIPK?
The strongest Open Targets associations for LIPK are lung adenocarcinoma, cutaneous melanoma, squamous cell lung carcinoma, PHF-tau measurement and self reported educational attainment.
How long is the LIPK protein?
The Homo sapiens LIPK protein (UniProt Q5VXJ0) is 399 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VXJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VXJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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