Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 (NKAIN2)
Homo sapiens — UniProt Q5VXU1
Data last refreshed: (UniProt release unknown)
Key facts
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 (NKAIN2) is a protein from Homo sapiens identified by UniProt accession Q5VXU1, 208 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q5VXU1; gene symbol NKAIN2.
- Organism: Homo sapiens.
- Length: 208 amino acids.
- Top disease associations (Open Targets): schizophrenia, unipolar depression and sex interaction measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 |
|---|---|
| UniProt accession | Q5VXU1 |
| Gene | NKAIN2 |
| Organism | Homo sapiens |
| Length | 208 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.46
- unipolar depression · score 0.46
- sex interaction measurement · score 0.46
- bipolar disorder · score 0.46
- protein measurement · score 0.42
- body mass index · score 0.36
- fasting blood insulin measurement · score 0.34
- stomatitis · score 0.33
- body weight · score 0.33
- insomnia measurement · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VXU1-F1 | alphafold | PREDICTED | 76.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VXU1.
Amino-acid sequence (208 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NKAIN2?
The strongest Open Targets associations for NKAIN2 are schizophrenia, unipolar depression, sex interaction measurement, bipolar disorder and protein measurement.
How long is the NKAIN2 protein?
The Homo sapiens NKAIN2 protein (UniProt Q5VXU1) is 208 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VXU1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VXU1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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