UL16-binding protein 6 (RAET1L)
Homo sapiens — UniProt Q5VY80
Data last refreshed: (UniProt release unknown)
Key facts
UL16-binding protein 6 (RAET1L) is a protein from Homo sapiens identified by UniProt accession Q5VY80, 246 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q5VY80; gene symbol RAET1L.
- Organism: Homo sapiens.
- Length: 246 amino acids.
- Top disease associations (Open Targets): alopecia areata, basal cell carcinoma and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UL16-binding protein 6 |
|---|---|
| UniProt accession | Q5VY80 |
| Gene | RAET1L |
| Organism | Homo sapiens |
| Length | 246 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- alopecia areata · score 0.32
- basal cell carcinoma · score 0.26
- neurodegenerative disease · score 0.26
- body fat percentage · score 0.20
- blood protein measurement · score 0.07
- non-small cell lung carcinoma · score 0.05
- lymphocyte count · score 0.05
- colorectal cancer · score 0.03
- eosinophil count · score 0.02
- chronic lymphocytic leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VY80-F1 | alphafold | PREDICTED | 82.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VY80.
Amino-acid sequence (246 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAET1L?
The strongest Open Targets associations for RAET1L are alopecia areata, basal cell carcinoma, neurodegenerative disease, body fat percentage and blood protein measurement.
How long is the RAET1L protein?
The Homo sapiens RAET1L protein (UniProt Q5VY80) is 246 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VY80 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VY80 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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