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Spermatogenesis-associated protein 31G1 (SPATA31G1)

Homo sapiens — UniProt Q5VYM1

Gene: SPATA31G1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Spermatogenesis-associated protein 31G1 (SPATA31G1) is a protein from Homo sapiens identified by UniProt accession Q5VYM1, 1079 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

  • UniProt accession: Q5VYM1; gene symbol SPATA31G1.
  • Organism: Homo sapiens.
  • Length: 1079 amino acids.
  • Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin and platelet count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSpermatogenesis-associated protein 31G1
UniProt accessionQ5VYM1
GeneSPATA31G1
OrganismHomo sapiens
Length1079 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (17)

Diseases linked to this target (Open Targets).

  • mean corpuscular volume · score 0.29
  • mean corpuscular hemoglobin · score 0.26
  • platelet count · score 0.24
  • monocyte count · score 0.23
  • mean corpuscular hemoglobin concentration · score 0.20
  • mean reticulocyte volume · score 0.18
  • platelet crit · score 0.11
  • mean platelet volume · score 0.09
  • myeloid white cell count · score 0.09
  • neutrophil count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5VYM1-F1alphafoldPREDICTED39.46—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYM1.

Amino-acid sequence (1079 residues)

MEWLLEDLLG AKGDMGLLWG QLTHALACRH CGSSCFQSPG NLVTLFLFVV WQIQRWWQLG RLRQLHPWCS GNMVQGKELP LLHRVAFLDH LCKQKSEVEE EGEEEEEGED EASLDPLKPC SPTKEAPTGE QATPAPPQPS CGSEGLLKAI GIPEQTVMQP VSPSRSFPIF QILTSFPVRH KIASGNRQQQ RKSQLFWGLP SLHSESLEAI FLSSGGPSPL KWSVCSSVFF NKLAFLPRSN LLLPQYHSSA QFSTHGAHTM EDLEGMAPDP QLLPPPSSPS VSSLLLHLRP FPVDHKGVLS GAEAPTQSPG TSPLEVLPGY ETHLETTGHK KMPQAFEPPM PPPCQSPASL SEPRKVSPEG GLAISKDFWG TVGYREKPQA SESSMPVPCP PLDSLPELQR ESSLEDPSRY KPQWECRENS GNLWAFESPV LDLNPELSGT SPECVPPASE TPWKGMQSRE NIWVPADPVS PPSLPSVPLL ESLVMGPQGV LSESKALWET MGQKENLWAS DSPDPVHSTP PTTLMEPHRI NPGECLATSE ATWKDTEHSR NSSASRSPSL ALSPPPALAP ELLRVRSMGV LSDSEARCGD IQKTKNSWAS KHPACNLPQD LHGASPLGVL SDSQSIVGEM EQKENCVPVF PGRGSSPSSN SVSKSHVSEP IADQSNYKPD GEAVEQRKNH WATELPAPSS LSTPLPEPHI DLELVWRNVQ QREVPQGPSP LAVDPLHPVP QPPTLAEAVK IERTHPGLPK GVTCPGVKAE APLSQRWTVP ELLTHPGIHA WQWSRELKLR LKKLRQSPAS RAPGPSQSFC SSPILSSTIP DFWGLPSCPP QQIYPPNPCP HSSSCHPQEV QRTVPQPVQS SHCHHFQSSS QLQPQESGRA EQGSQRGEKM KGKMVSQVPS QGPCVHMEAG VDYLSPGPGE PSNSKVLVSG KRKDKASASS SAKKREHPRK PKAGDHRRGT ARLGLSTVTG KNHPAQARSL VEAPVSTFPQ RSQHRGQSSQ HTALPQLLLP KASGPQDQPE AGRRASDILT PRHCKHCPWA HMEKYLSFPT LKASLTRGLQ KVLAKCLDNH RPLPTKSSQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SPATA31G1?

The strongest Open Targets associations for SPATA31G1 are mean corpuscular volume, mean corpuscular hemoglobin, platelet count, monocyte count and mean corpuscular hemoglobin concentration.

How long is the SPATA31G1 protein?

The Homo sapiens SPATA31G1 protein (UniProt Q5VYM1) is 1079 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5VYM1
GeneSPATA31G1
OrganismHomo sapiens
Length1079
Binders0
Diseases17
View on UniProt