Spermatogenesis-associated protein 31A3 (SPATA31A3)

Homo sapiens — UniProt Q5VYP0

Gene: SPATA31A3Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Spermatogenesis-associated protein 31A3 (SPATA31A3) is a protein from Homo sapiens identified by UniProt accession Q5VYP0, 1347 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

UniProt accession: Q5VYP0; gene symbol SPATA31A3.
Organism: Homo sapiens.
Length: 1347 amino acids.
Top disease associations (Open Targets): primary biliary cirrhosis.
3D structure: AlphaFold model available.

Target properties

Protein name	Spermatogenesis-associated protein 31A3
UniProt accession	Q5VYP0
Gene	SPATA31A3
Organism	Homo sapiens
Length	1347 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

primary biliary cirrhosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VYP0-F1	alphafold	PREDICTED	38.51	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYP0.

Amino-acid sequence (1347 residues)

MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS LLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVALPLGTV PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF TNRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE QHIKKWIIQH WGNLGRIQES LDLMQLQDES PGTSQAKGKP SPWQSSMSTG ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP RKLCLMEEVV SEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRK PNCQGSCKSQ RPMFPPIHKS EKFRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SPATA31A3?

The strongest Open Targets associations for SPATA31A3 are primary biliary cirrhosis.

How long is the SPATA31A3 protein?

The Homo sapiens SPATA31A3 protein (UniProt Q5VYP0) is 1347 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5VYP0 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5VYP0 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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