Terminal uridylyltransferase 7 (TUT7)

Homo sapiens — UniProt Q5VYS8

Gene: TUT7Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Terminal uridylyltransferase 7 (TUT7) is a protein from Homo sapiens identified by UniProt accession Q5VYS8, 1495 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

UniProt accession: Q5VYS8; gene symbol TUT7.
Organism: Homo sapiens.
Length: 1495 amino acids.
Top disease associations (Open Targets): body height, sex hormone-binding globulin measurement and Red cell distribution width.
3D structure: AlphaFold model available.

Target properties

Protein name	Terminal uridylyltransferase 7
UniProt accession	Q5VYS8
Gene	TUT7
Organism	Homo sapiens
Length	1495 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

body height · score 0.43
sex hormone-binding globulin measurement · score 0.42
Red cell distribution width · score 0.34
FEV/FVC ratio · score 0.30
testosterone measurement · score 0.29
Immature Reticulocyte Fraction Measurement · score 0.28
body mass index · score 0.27
cortical surface area measurement · score 0.26
reticulocyte count · score 0.26
mathematical ability · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VYS8-F1	alphafold	PREDICTED	66.09	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYS8.

Amino-acid sequence (1495 residues)

MGDTAKPYFV KRTKDRGTMD DDDFRRGHPQ QDYLIIDDHA KGHGSKMEKG LQKKKITPGN YGNTPRKGPC AVSSNPYAFK NPIYSQPAWM NDSHKDQSKR WLSDEHTGNS DNWREFKPGP RIPVINRQRK DSFQENEDGY RWQDTRGCRT VRRLFHKDLT SLETTSEMEA GSPENKKQRS RPRKPRKTRN EENEQDGDLE GPVIDESVLS TKELLGLQQA EERLKRDCID RLKRRPRNYP TAKYTCRLCD VLIESIAFAH KHIKEKRHKK NIKEKQEEEL LTTLPPPTPS QINAVGIAID KVVQEFGLHN ENLEQRLEIK RIMENVFQHK LPDCSLRLYG SSCSRLGFKN SDVNIDIQFP AIMSQPDVLL LVQECLKNSD SFIDVDADFH ARVPVVVCRE KQSGLLCKVS AGNENACLTT KHLTALGKLE PKLVPLVIAF RYWAKLCSID RPEEGGLPPY VFALMAIFFL QQRKEPLLPV YLGSWIEGFS LSKLGNFNLQ DIEKDVVIWE HTDSAAGDTG ITKEEAPRET PIKRGQVSLI LDVKHQPSVP VGQLWVELLR FYALEFNLAD LVISIRVKEL VSRELKDWPK KRIAIEDPYS VKRNVARTLN SQPVFEYILH CLRTTYKYFA LPHKITKSSL LKPLNAITCI SEHSKEVINH HPDVQTKDDK LKNSVLAQGP GATSSAANTC KVQPLTLKET AESFGSPPKE EMGNEHISVH PENSDCIQAD VNSDDYKGDK VYHPETGRKN EKEKVGRKGK HLLTVDQKRG EHVVCGSTRN NESESTLDLE GFQNPTAKEC EGLATLDNKA DLDGESTEGT EELEDSLNHF THSVQGQTSE MIPSDEEEED DEEEEEEEEP RLTINQREDE DGMANEDELD NTYTGSGDED ALSEEDDELG EAAKYEDVKE CGKHVERALL VELNKISLKE ENVCEEKNSP VDQSDFFYEF SKLIFTKGKS PTVVCSLCKR EGHLKKDCPE DFKRIQLEPL PPLTPKFLNI LDQVCIQCYK DFSPTIIEDQ AREHIRQNLE SFIRQDFPGT KLSLFGSSKN GFGFKQSDLD VCMTINGLET AEGLDCVRTI EELARVLRKH SGLRNILPIT TAKVPIVKFF HLRSGLEVDI SLYNTLALHN TRLLSAYSAI DPRVKYLCYT MKVFTKMCDI GDASRGSLSS YAYTLMVLYF LQQRNPPVIP VLQEIYKGEK KPEIFVDGWN IYFFDQIDEL PTYWSECGKN TESVGQLWLG LLRFYTEEFD FKEHVISIRR KSLLTTFKKQ WTSKYIVIED PFDLNHNLGA GLSRKMTNFI MKAFINGRRV FGIPVKGFPK DYPSKMEYFF DPDVLTEGEL APNDRCCRIC GKIGHFMKDC PMRRKVRRRR DQEDALNQRY PENKEKRSKE DKEIHNKYTE REVSTKEDKP IQCTPQKAKP MRAAADLGRE KILRPPVEKW KRQDDKDLRE KRCFICGREG HIKKECPQFK GSSGSLSSKY MTQGKASAKR TQQES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TUT7?

The strongest Open Targets associations for TUT7 are body height, sex hormone-binding globulin measurement, Red cell distribution width, FEV/FVC ratio and testosterone measurement.

How long is the TUT7 protein?

The Homo sapiens TUT7 protein (UniProt Q5VYS8) is 1495 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5VYS8 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5VYS8 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

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