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Protein SLX4IP (SLX4IP)

Homo sapiens — UniProt Q5VYV7

Gene: SLX4IPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein SLX4IP (SLX4IP) is a protein from Homo sapiens identified by UniProt accession Q5VYV7, 408 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

  • UniProt accession: Q5VYV7; gene symbol SLX4IP.
  • Organism: Homo sapiens.
  • Length: 408 amino acids.
  • Top disease associations (Open Targets): diastolic blood pressure, heel bone mineral density and appendicular lean mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein SLX4IP
UniProt accessionQ5VYV7
GeneSLX4IP
OrganismHomo sapiens
Length408 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (74)

Diseases linked to this target (Open Targets).

  • diastolic blood pressure · score 0.46
  • heel bone mineral density · score 0.40
  • appendicular lean mass · score 0.39
  • vital capacity · score 0.38
  • reticulocyte count · score 0.37
  • hematocrit · score 0.34
  • cystatin C measurement · score 0.34
  • lymphocyte count · score 0.34
  • forced expiratory volume · score 0.33
  • pulse pressure measurement · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5VYV7-F1alphafoldPREDICTED54.74—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYV7.

Amino-acid sequence (408 residues)

MASKKFAVKC GNFAVLVDLH ILPQGSNKDT SWFSEQKKEE VCLLLKETID SRVQEYLEVR KQHRPSNAEF TRSNPLSLKG YGFQITAYFL KRGIRLRCIR STQNAELCVF PDRFVVCVSQ LAFSRDLLAS QNEDLTERVL HGVSDYFAEC AESSLPPSAK LRRNALKEIV KRTETKSSVT SKSQTRRDTV ETSSDSVIAE IARRRNDGQA SSSPPSESMG QAKDSIKAAE SHWGLPVQKL EKVNQTQPED TSGQQKPHPG ERLKTGLLSR SPVCSCESAS PCPKQSPRVA KTQQKRRNCS SAEDFDHHGR VSLGSDRLVP REIIVEKSKA VRVLPASELS DPGLLLKQDL AKTTSKEELH VLESLSSRHL MKNNPGQAQQ TGLATNTERL STIQNSPTKK RKKYERGH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLX4IP?

The strongest Open Targets associations for SLX4IP are diastolic blood pressure, heel bone mineral density, appendicular lean mass, vital capacity and reticulocyte count.

How long is the SLX4IP protein?

The Homo sapiens SLX4IP protein (UniProt Q5VYV7) is 408 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5VYV7
GeneSLX4IP
OrganismHomo sapiens
Length408
Binders0
Diseases74
View on UniProt