Renalase (RNLS)
Homo sapiens — UniProt Q5VYX0
Data last refreshed: (UniProt release unknown)
Key facts
Renalase (RNLS) is a protein from Homo sapiens identified by UniProt accession Q5VYX0, 342 residues long. MolForge cross-references it against 0 known binders and 158 disease associations.
- UniProt accession: Q5VYX0; gene symbol RNLS.
- Organism: Homo sapiens.
- Length: 342 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, hematocrit and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Renalase |
|---|---|
| UniProt accession | Q5VYX0 |
| Gene | RNLS |
| Organism | Homo sapiens |
| Length | 342 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (158)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.45
- hematocrit · score 0.44
- erythrocyte count · score 0.43
- creatinine measurement · score 0.42
- type 1 diabetes mellitus · score 0.41
- refractive error measurement · score 0.40
- cortical surface area measurement · score 0.39
- corneal topography · score 0.38
- prostate carcinoma · score 0.38
- cortical thickness · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VYX0-F1 | alphafold | PREDICTED | 96.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYX0.
Amino-acid sequence (342 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNLS?
The strongest Open Targets associations for RNLS are hemoglobin measurement, hematocrit, erythrocyte count, creatinine measurement and type 1 diabetes mellitus.
How long is the RNLS protein?
The Homo sapiens RNLS protein (UniProt Q5VYX0) is 342 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VYX0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VYX0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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