Ankyrin repeat domain-containing protein 22 (ANKRD22)
Homo sapiens — UniProt Q5VYY1
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 22 (ANKRD22) is a protein from Homo sapiens identified by UniProt accession Q5VYY1, 191 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q5VYY1; gene symbol ANKRD22.
- Organism: Homo sapiens.
- Length: 191 amino acids.
- Top disease associations (Open Targets): tumor necrosis factor receptor superfamily member 6 measurement, neoplasm and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 22 |
|---|---|
| UniProt accession | Q5VYY1 |
| Gene | ANKRD22 |
| Organism | Homo sapiens |
| Length | 191 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- tumor necrosis factor receptor superfamily member 6 measurement · score 0.19
- neoplasm · score 0.09
- non-small cell lung carcinoma · score 0.08
- Sepsis · score 0.05
- central nervous system cancer · score 0.04
- Crohn's disease · score 0.03
- septic shock · score 0.03
- Leishmaniasis · score 0.03
- lung adenocarcinoma · score 0.02
- cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VYY1-F1 | alphafold | PREDICTED | 93.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VYY1.
Amino-acid sequence (191 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD22?
The strongest Open Targets associations for ANKRD22 are tumor necrosis factor receptor superfamily member 6 measurement, neoplasm, non-small cell lung carcinoma, Sepsis and central nervous system cancer.
How long is the ANKRD22 protein?
The Homo sapiens ANKRD22 protein (UniProt Q5VYY1) is 191 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VYY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VYY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.