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Tudor domain-containing protein 10 (TDRD10)

Homo sapiens — UniProt Q5VZ19

Gene: TDRD10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Tudor domain-containing protein 10 (TDRD10) is a protein from Homo sapiens identified by UniProt accession Q5VZ19, 366 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

  • UniProt accession: Q5VZ19; gene symbol TDRD10.
  • Organism: Homo sapiens.
  • Length: 366 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, interleukin 6 receptor subunit alpha measurement and interleukin-6 receptor measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTudor domain-containing protein 10
UniProt accessionQ5VZ19
GeneTDRD10
OrganismHomo sapiens
Length366 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (42)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.35
  • interleukin 6 receptor subunit alpha measurement · score 0.31
  • interleukin-6 receptor measurement · score 0.18
  • blood protein measurement · score 0.17
  • leukocyte count · score 0.10
  • interleukin-6 measurement · score 0.08
  • C-reactive protein measurement · score 0.07
  • alkaline phosphatase measurement · score 0.06
  • serum amyloid A-1 protein measurement · score 0.06
  • Red cell distribution width · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5VZ19-F1alphafoldPREDICTED71.74—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VZ19.

Amino-acid sequence (366 residues)

MSWNISHPQL SDKLFGKNGV LEEQKSPGFK KRETEVYVGN LPLDISKEEI LYLLKDFNPL DVHKIQNGCK CFAFVDLGSM QKVTLAIQEL NGKLFHKRKL FVNTSKRPPK RTPDMIQQPR APLVLEKASG EGFGKTAAII QLAPKAPVDL CETEKLRAAF FAVPLEMRGS FLVLLLRECF RDLSWLALIH SVRGEAGLLV TSIVPKTPFF WAMHVTEALH QNMQALFSTL AQAEEQQPYL EGSTVMRGTR CLAEYHLGDY GHAWNRCWVL DRVDTWAVVM FIDFGQLATI PVQSLRSLDS DDFWTIPPLT QPFMLEKDIL SSYEVVHRIL KGKITGALNS AVTAPASNLA VVPPLLPLGC LQQAAA

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TDRD10?

The strongest Open Targets associations for TDRD10 are neurodegenerative disease, interleukin 6 receptor subunit alpha measurement, interleukin-6 receptor measurement, blood protein measurement and leukocyte count.

How long is the TDRD10 protein?

The Homo sapiens TDRD10 protein (UniProt Q5VZ19) is 366 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5VZ19
GeneTDRD10
OrganismHomo sapiens
Length366
Binders0
Diseases42
View on UniProt