Janus kinase and microtubule-interacting protein 3 (JAKMIP3)
Homo sapiens — UniProt Q5VZ66
Data last refreshed: (UniProt release unknown)
Key facts
Janus kinase and microtubule-interacting protein 3 (JAKMIP3) is a protein from Homo sapiens identified by UniProt accession Q5VZ66, 844 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q5VZ66; gene symbol JAKMIP3.
- Organism: Homo sapiens.
- Length: 844 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuritic plaque measurement and depressive disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Janus kinase and microtubule-interacting protein 3 |
|---|---|
| UniProt accession | Q5VZ66 |
| Gene | JAKMIP3 |
| Organism | Homo sapiens |
| Length | 844 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- neuritic plaque measurement · score 0.31
- depressive disorder · score 0.28
- drug use measurement · score 0.27
- body mass index · score 0.24
- body fat percentage · score 0.24
- cortical thickness · score 0.22
- adolescent idiopathic scoliosis · score 0.21
- mathematical ability · score 0.19
- lean body mass · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VZ66-F1 | alphafold | PREDICTED | 78.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VZ66.
Amino-acid sequence (844 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JAKMIP3?
The strongest Open Targets associations for JAKMIP3 are neurodegenerative disease, neuritic plaque measurement, depressive disorder, drug use measurement and body mass index.
How long is the JAKMIP3 protein?
The Homo sapiens JAKMIP3 protein (UniProt Q5VZ66) is 844 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VZ66 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VZ66 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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