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Zinc finger MYM-type protein 4 (ZMYM4)

Homo sapiens — UniProt Q5VZL5

Gene: ZMYM4Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger MYM-type protein 4 (ZMYM4) is a protein from Homo sapiens identified by UniProt accession Q5VZL5, 1548 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

  • UniProt accession: Q5VZL5; gene symbol ZMYM4.
  • Organism: Homo sapiens.
  • Length: 1548 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and monocyte percentage of leukocytes.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger MYM-type protein 4
UniProt accessionQ5VZL5
GeneZMYM4
OrganismHomo sapiens
Length1548 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (30)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.46
  • sex hormone-binding globulin measurement · score 0.34
  • monocyte percentage of leukocytes · score 0.32
  • waist-hip ratio · score 0.20
  • type 1 diabetes mellitus · score 0.05
  • systemic scleroderma · score 0.05
  • systemic lupus erythematosus · score 0.05
  • Eczematoid dermatitis · score 0.05
  • cholesterol-ester transfer protein deficiency · score 0.04
  • Combined hyperlipidemia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5VZL5-F1alphafoldPREDICTED58.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VZL5.

Amino-acid sequence (1548 residues)

MAEREVESGP RKRFEQKSGA VFDEIVENCG GIMDTEMSED IDHNLTPTLD SMSYGMPNQT GSENSLLDED DYFLNSGDLA GIPVVGSDNE DEQDFSSKDN LVSSIHTDDS LEVERRVTQH ESDNENEIQI QNKLKKDFPK QFDQVSVFKS IRKDFSLVRE NSKETFSGKE KNRDLTYERE KRLDKPHKDL DSRLKSSFFD KAANQVEETL HTHLPQTPET NFRDSSYPFA NKESIGSELG NSFASNIRIK EEPLDDEYDK AMAPQQGLLD KIKDEPDNAQ EYSHGQQQKT QEGELKISAV FSVSGSPLAP QLTTGFQPSL ASSGMNKMLP SVPATAVRVS CSGCKKILQK GQTAYQRKGS TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK DVISAQFENT TTSKDFCSQS CLSTYELKKK PIVTINTNSI STKCSMCQKN AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN LTMNCCENCG GYCYSGSGQC HMLQIEGQSK KFCSSSCITA YKQKSAKITP CALCKSLRSS AEMIENTNSL GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG STVSAGGGST SAVSPTSISS SAAAGLQRLA AQSQHVGFAR SVVKLKCQHC NRLFATKPEL LDYKGKMFQF CGKNCSDEYK KINNVMAMCE YCKIEKIVKE TVRFSGADKS FCSEGCKLLY KHDLAKRWGN HCKMCSYCLQ TSPKLVQNNL GGKVEEFCCE ECMSKYTVLF YQMAKCDACK RQGKLSESLK WRGEMKHFCN LLCILMFCNQ QSVCDPPSQN NAANISMVQA ASAGPPSLRK DSTPVIANVV SLASAPAAQP TVNSNSVLQG AVPTVTAKII GDASTQTDAL KLPPSQPPRL LKNKALLCKP ITQTKATSCK PHTQNKECQT EDTPSQPQII VVPVPVPVFV PIPLHLYTQY APVPFGIPVP MPVPMLIPSS MDSEDKVTES IEDIKEKLPT HPFEADLLEM AEMIAEDEEK KTLSQGESQT SEHELFLDTK IFEKDQGSTY SGDLESEAVS TPHSWEEELN HYALKSNAVQ EADSELKQFS KGETEQDLEA DFPSDSFDPL NKGQGIQARS RTRRRHRDGF PQPRRRGRKK SIVAVEPRSL IQGAFQGCSV SGMTLKYMYG VNAWKNWVQW KNAKEEQGDL KCGGVEQASS SPRSDPLGST QDHALSQESS EPGCRVRSIK LKEDILSCTF AELSLGLCQF IQEVRRPNGE KYDPDSILYL CLGIQQYLFE NGRIDNIFTE PYSRFMIELT KLLKIWEPTI LPNGYMFSRI EEEHLWECKQ LGAYSPIVLL NTLLFFNTKY FQLKNVTEHL KLSFAHVMRR TRTLKYSTKM TYLRFFPPLQ KQESEPDKLT VGKRKRNEDD EVPVGVEMAE NTDNPLRCPV RLYEFYLSKC SESVKQRNDV FYLQPERSCV PNSPMWYSTF PIDPGTLDTM LTRILMVREV HEELAKAKSE DSDVELSD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZMYM4?

The strongest Open Targets associations for ZMYM4 are neurodegenerative disease, sex hormone-binding globulin measurement, monocyte percentage of leukocytes, waist-hip ratio and type 1 diabetes mellitus.

How long is the ZMYM4 protein?

The Homo sapiens ZMYM4 protein (UniProt Q5VZL5) is 1548 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5VZL5
GeneZMYM4
OrganismHomo sapiens
Length1548
Binders0
Diseases30
View on UniProt