Lipase member J (LIPJ)
Homo sapiens — UniProt Q5W064
Data last refreshed: (UniProt release unknown)
Key facts
Lipase member J (LIPJ) is a protein from Homo sapiens identified by UniProt accession Q5W064, 366 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q5W064; gene symbol LIPJ.
- Organism: Homo sapiens.
- Length: 366 amino acids.
- Top disease associations (Open Targets): reading and spelling ability, aortic vascular smooth muscle cell calcification measurement and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lipase member J |
|---|---|
| UniProt accession | Q5W064 |
| Gene | LIPJ |
| Organism | Homo sapiens |
| Length | 366 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- reading and spelling ability · score 0.29
- aortic vascular smooth muscle cell calcification measurement · score 0.20
- erythrocyte count · score 0.15
- cutaneous melanoma · score 0.11
- hemoglobin measurement · score 0.10
- squamous cell lung carcinoma · score 0.10
- creatinine measurement · score 0.10
- cortical surface area measurement · score 0.10
- cortical thickness · score 0.09
- hematocrit · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5W064-F1 | alphafold | PREDICTED | 92.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5W064.
Amino-acid sequence (366 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LIPJ?
The strongest Open Targets associations for LIPJ are reading and spelling ability, aortic vascular smooth muscle cell calcification measurement, erythrocyte count, cutaneous melanoma and hemoglobin measurement.
How long is the LIPJ protein?
The Homo sapiens LIPJ protein (UniProt Q5W064) is 366 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5W064 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5W064 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.