Transmembrane protein 236 (TMEM236)
Homo sapiens — UniProt Q5W0B7
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 236 (TMEM236) is a protein from Homo sapiens identified by UniProt accession Q5W0B7, 351 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q5W0B7; gene symbol TMEM236.
- Organism: Homo sapiens.
- Length: 351 amino acids.
- Top disease associations (Open Targets): aspartate aminotransferase measurement, body height and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 236 |
|---|---|
| UniProt accession | Q5W0B7 |
| Gene | TMEM236 |
| Organism | Homo sapiens |
| Length | 351 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.47
- body height · score 0.35
- serum albumin measurement · score 0.34
- total blood protein measurement · score 0.34
- apolipoprotein A 1 measurement · score 0.33
- neurodegenerative disease · score 0.26
- hemoglobin measurement · score 0.23
- blood protein measurement · score 0.21
- hematocrit · score 0.15
- heel bone mineral density · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5W0B7-F1 | alphafold | PREDICTED | 73.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5W0B7.
Amino-acid sequence (351 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM236?
The strongest Open Targets associations for TMEM236 are aspartate aminotransferase measurement, body height, serum albumin measurement, total blood protein measurement and apolipoprotein A 1 measurement.
How long is the TMEM236 protein?
The Homo sapiens TMEM236 protein (UniProt Q5W0B7) is 351 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5W0B7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5W0B7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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