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Palmitoyltransferase ZDHHC20 (ZDHHC20)

Homo sapiens — UniProt Q5W0Z9

Gene: ZDHHC20Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Palmitoyltransferase ZDHHC20 (ZDHHC20) is a protein from Homo sapiens identified by UniProt accession Q5W0Z9, 365 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

  • UniProt accession: Q5W0Z9; gene symbol ZDHHC20.
  • Organism: Homo sapiens.
  • Length: 365 amino acids.
  • Top disease associations (Open Targets): hemoglobin measurement, COVID-19 and chronic bronchitis.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePalmitoyltransferase ZDHHC20
UniProt accessionQ5W0Z9
GeneZDHHC20
OrganismHomo sapiens
Length365 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • hemoglobin measurement · score 0.38
  • COVID-19 · score 0.37
  • chronic bronchitis · score 0.22
  • PR interval · score 0.16
  • heel bone mineral density · score 0.08
  • pancreatic neoplasm · score 0.07
  • electrocardiography · score 0.07
  • Hypomaturation amelogenesis imperfecta · score 0.07
  • refractive error measurement · score 0.07
  • Hypoplastic amelogenesis imperfecta · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5W0Z9-F1alphafoldPREDICTED85.39—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5W0Z9.

Amino-acid sequence (365 residues)

MAPWTLWRCC QRVVGWVPVL FITFVVVWSY YAYVVELCVF TIFGNEENGK TVVYLVAFHL FFVMFVWSYW MTIFTSPASP SKEFYLSNSE KERYEKEFSQ ERQQEILRRA ARALPIYTTS ASKTIRYCEK CQLIKPDRAH HCSACDSCIL KMDHHCPWVN NCVGFSNYKF FLLFLLYSLL YCLFVAATVL EYFIKFWTNE LTDTRAKFHV LFLFFVSAMF FISVLSLFSY HCWLVGKNRT TIESFRAPTF SYGPDGNGFS LGCSKNWRQV FGDEKKYWLL PIFSSLGDGC SFPTRLVGMD PEQASVTNQN EYARSSGSNQ PFPIKPLSES KNRLLDSESQ WLENGAEEGI VKSGTNNHVT VAIEN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZDHHC20?

The strongest Open Targets associations for ZDHHC20 are hemoglobin measurement, COVID-19, chronic bronchitis, PR interval and heel bone mineral density.

How long is the ZDHHC20 protein?

The Homo sapiens ZDHHC20 protein (UniProt Q5W0Z9) is 365 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5W0Z9
GeneZDHHC20
OrganismHomo sapiens
Length365
Binders0
Diseases62
View on UniProt