Regulated endocrine-specific protein 18 (RESP18)
Homo sapiens — UniProt Q5W5W9
Data last refreshed: (UniProt release unknown)
Key facts
Regulated endocrine-specific protein 18 (RESP18) is a protein from Homo sapiens identified by UniProt accession Q5W5W9, 228 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q5W5W9; gene symbol RESP18.
- Organism: Homo sapiens.
- Length: 228 amino acids.
- Top disease associations (Open Targets): body mass index, body weight and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Regulated endocrine-specific protein 18 |
|---|---|
| UniProt accession | Q5W5W9 |
| Gene | RESP18 |
| Organism | Homo sapiens |
| Length | 228 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- body mass index · score 0.28
- body weight · score 0.20
- body fat percentage · score 0.10
- body height · score 0.08
- age-related macular degeneration · score 0.07
- X-linked retinal dysplasia · score 0.06
- Familial exudative vitreoretinopathy · score 0.06
- retinitis pigmentosa · score 0.06
- severe early-childhood-onset retinal dystrophy · score 0.05
- hypertriglyceridemia 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5W5W9-F1 | alphafold | PREDICTED | 45.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5W5W9.
Amino-acid sequence (228 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RESP18?
The strongest Open Targets associations for RESP18 are body mass index, body weight, body fat percentage, body height and age-related macular degeneration.
How long is the RESP18 protein?
The Homo sapiens RESP18 protein (UniProt Q5W5W9) is 228 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5W5W9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5W5W9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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