Tetratricopeptide repeat protein 23 (TTC23)
Homo sapiens — UniProt Q5W5X9
Data last refreshed: (UniProt release unknown)
Key facts
Tetratricopeptide repeat protein 23 (TTC23) is a protein from Homo sapiens identified by UniProt accession Q5W5X9, 447 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q5W5X9; gene symbol TTC23.
- Organism: Homo sapiens.
- Length: 447 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, PHF-tau measurement and gestational age.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetratricopeptide repeat protein 23 |
|---|---|
| UniProt accession | Q5W5X9 |
| Gene | TTC23 |
| Organism | Homo sapiens |
| Length | 447 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.33
- PHF-tau measurement · score 0.13
- gestational age · score 0.03
- parental genotype effect measurement · score 0.03
- hemoglobin measurement · score 0.03
- Varicose veins · score 0.02
- erythrocyte count · score 0.02
- red blood cell density measurement · score 0.02
- mean corpuscular hemoglobin concentration · score 0.02
- hematocrit · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5W5X9-F1 | alphafold | PREDICTED | 85.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5W5X9.
Amino-acid sequence (447 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTC23?
The strongest Open Targets associations for TTC23 are FEV/FVC ratio, PHF-tau measurement, gestational age, parental genotype effect measurement and hemoglobin measurement.
How long is the TTC23 protein?
The Homo sapiens TTC23 protein (UniProt Q5W5X9) is 447 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5W5X9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5W5X9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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