Keratin, type II cytoskeletal 79 (KRT79)
Homo sapiens — UniProt Q5XKE5
Data last refreshed: (UniProt release unknown)
Key facts
Keratin, type II cytoskeletal 79 (KRT79) is a protein from Homo sapiens identified by UniProt accession Q5XKE5, 535 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q5XKE5; gene symbol KRT79.
- Organism: Homo sapiens.
- Length: 535 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, prostate adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin, type II cytoskeletal 79 |
|---|---|
| UniProt accession | Q5XKE5 |
| Gene | KRT79 |
| Organism | Homo sapiens |
| Length | 535 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- neuroblastoma · score 0.13
- prostate carcinoma · score 0.08
- aspartate aminotransferase measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5XKE5-F1 | alphafold | PREDICTED | 68.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XKE5.
Amino-acid sequence (535 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRT79?
The strongest Open Targets associations for KRT79 are neurodegenerative disease, prostate adenocarcinoma, ovarian cancer, head and neck squamous cell carcinoma and glioblastoma multiforme.
How long is the KRT79 protein?
The Homo sapiens KRT79 protein (UniProt Q5XKE5) is 535 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5XKE5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5XKE5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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