Protein FAM219B (FAM219B)
Homo sapiens — UniProt Q5XKK7
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM219B (FAM219B) is a protein from Homo sapiens identified by UniProt accession Q5XKK7, 198 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q5XKK7; gene symbol FAM219B.
- Organism: Homo sapiens.
- Length: 198 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin and monocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM219B |
|---|---|
| UniProt accession | Q5XKK7 |
| Gene | FAM219B |
| Organism | Homo sapiens |
| Length | 198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.31
- mean corpuscular hemoglobin · score 0.28
- monocyte percentage of leukocytes · score 0.19
- smoking status measurement · score 0.18
- diastolic blood pressure · score 0.18
- systolic blood pressure · score 0.16
- Red cell distribution width · score 0.12
- hemoglobin measurement · score 0.11
- platelet count · score 0.10
- lymphocyte percentage of leukocytes · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5XKK7-F1 | alphafold | PREDICTED | 65.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XKK7.
Amino-acid sequence (198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM219B?
The strongest Open Targets associations for FAM219B are mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, monocyte percentage of leukocytes, smoking status measurement and diastolic blood pressure.
How long is the FAM219B protein?
The Homo sapiens FAM219B protein (UniProt Q5XKK7) is 198 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5XKK7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5XKK7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.