MICOS complex subunit MIC13 (MICOS13)
Homo sapiens — UniProt Q5XKP0
Data last refreshed: (UniProt release unknown)
Key facts
MICOS complex subunit MIC13 (MICOS13) is a protein from Homo sapiens identified by UniProt accession Q5XKP0, 118 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q5XKP0; gene symbol MICOS13.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): combined oxidative phosphorylation deficiency, mitochondrial disease and 3-methylglutaconic aciduria type 3.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MICOS complex subunit MIC13 |
|---|---|
| UniProt accession | Q5XKP0 |
| Gene | MICOS13 |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation deficiency · score 0.45
- mitochondrial disease · score 0.37
- 3-methylglutaconic aciduria type 3 · score 0.37
- genetic disorder · score 0.31
- cholesterol-ester transfer protein deficiency · score 0.04
- mean corpuscular hemoglobin concentration · score 0.04
- hypertriglyceridemia 2 · score 0.04
- Combined hyperlipidemia · score 0.04
- mean corpuscular hemoglobin · score 0.04
- pancreatic triacylglycerol lipase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5XKP0-F1 | alphafold | PREDICTED | 86.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XKP0.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MICOS13?
The strongest Open Targets associations for MICOS13 are combined oxidative phosphorylation deficiency, mitochondrial disease, 3-methylglutaconic aciduria type 3, genetic disorder and cholesterol-ester transfer protein deficiency.
How long is the MICOS13 protein?
The Homo sapiens MICOS13 protein (UniProt Q5XKP0) is 118 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5XKP0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5XKP0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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