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Protein VCF2 (VCF2)

Homo sapiens — UniProt Q5XKR9

Gene: VCF2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein VCF2 (VCF2) is a protein from Homo sapiens identified by UniProt accession Q5XKR9, 115 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

  • UniProt accession: Q5XKR9; gene symbol VCF2.
  • Organism: Homo sapiens.
  • Length: 115 amino acids.
  • Top disease associations (Open Targets): hypertension, megaloblastic anemia, folate-responsive and immunodeficiency 69.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein VCF2
UniProt accessionQ5XKR9
GeneVCF2
OrganismHomo sapiens
Length115 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (5)

Diseases linked to this target (Open Targets).

  • hypertension · score 0.04
  • megaloblastic anemia, folate-responsive · score 0.03
  • immunodeficiency 69 · score 0.03
  • NUT midline carcinoma · score 0.01
  • visceral Leishmaniasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5XKR9-F1alphafoldPREDICTED60.54—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XKR9.

Amino-acid sequence (115 residues)

MGGCPVRKRR RNGSKEGNHH STQPKRNKRN PIFQDSQDTE FSWSDNERSS SRINIPERAS GPEGNLNQIV TEPDANFPQF LHEGLSKPVY VINWFMSFGP EIKLNTSQQG RNQAV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with VCF2?

The strongest Open Targets associations for VCF2 are hypertension, megaloblastic anemia, folate-responsive, immunodeficiency 69, NUT midline carcinoma and visceral Leishmaniasis.

How long is the VCF2 protein?

The Homo sapiens VCF2 protein (UniProt Q5XKR9) is 115 amino acids long.

Browse: Targets: V · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5XKR9
GeneVCF2
OrganismHomo sapiens
Length115
Binders0
Diseases5
View on UniProt