F-box/WD repeat-containing protein 9 (FBXW9)
Homo sapiens — UniProt Q5XUX1
Data last refreshed: (UniProt release unknown)
Key facts
F-box/WD repeat-containing protein 9 (FBXW9) is a protein from Homo sapiens identified by UniProt accession Q5XUX1, 458 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q5XUX1; gene symbol FBXW9.
- Organism: Homo sapiens.
- Length: 458 amino acids.
- Top disease associations (Open Targets): endometrial cancer, lung adenocarcinoma and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box/WD repeat-containing protein 9 |
|---|---|
| UniProt accession | Q5XUX1 |
| Gene | FBXW9 |
| Organism | Homo sapiens |
| Length | 458 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.25
- lung adenocarcinoma · score 0.25
- breast adenocarcinoma · score 0.25
- urinary bladder cancer · score 0.24
- platelet component distribution width · score 0.21
- clear cell renal carcinoma · score 0.18
- squamous cell lung carcinoma · score 0.18
- platelet count · score 0.17
- acute lymphoblastic leukemia · score 0.14
- brain measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5XUX1-F1 | alphafold | PREDICTED | 84.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XUX1.
Amino-acid sequence (458 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXW9?
The strongest Open Targets associations for FBXW9 are endometrial cancer, lung adenocarcinoma, breast adenocarcinoma, urinary bladder cancer and platelet component distribution width.
How long is the FBXW9 protein?
The Homo sapiens FBXW9 protein (UniProt Q5XUX1) is 458 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5XUX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5XUX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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