F-box/WD repeat-containing protein 10 (FBXW10)
Homo sapiens — UniProt Q5XX13
Data last refreshed: (UniProt release unknown)
Key facts
F-box/WD repeat-containing protein 10 (FBXW10) is a protein from Homo sapiens identified by UniProt accession Q5XX13, 1052 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q5XX13; gene symbol FBXW10.
- Organism: Homo sapiens.
- Length: 1052 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, lung adenocarcinoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box/WD repeat-containing protein 10 |
|---|---|
| UniProt accession | Q5XX13 |
| Gene | FBXW10 |
| Organism | Homo sapiens |
| Length | 1052 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.25
- lung adenocarcinoma · score 0.25
- head and neck squamous cell carcinoma · score 0.25
- endometrial cancer · score 0.25
- ovarian cancer · score 0.25
- esophageal cancer · score 0.25
- gastric adenocarcinoma · score 0.25
- breast adenocarcinoma · score 0.25
- squamous cell lung carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5XX13-F1 | alphafold | PREDICTED | 61.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5XX13.
Amino-acid sequence (1052 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXW10?
The strongest Open Targets associations for FBXW10 are glioblastoma multiforme, lung adenocarcinoma, head and neck squamous cell carcinoma, endometrial cancer and ovarian cancer.
How long is the FBXW10 protein?
The Homo sapiens FBXW10 protein (UniProt Q5XX13) is 1052 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5XX13 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5XX13 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.