Leucine-rich repeat-containing protein 66 (LRRC66)
Homo sapiens — UniProt Q68CR7
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 66 (LRRC66) is a protein from Homo sapiens identified by UniProt accession Q68CR7, 880 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q68CR7; gene symbol LRRC66.
- Organism: Homo sapiens.
- Length: 880 amino acids.
- Top disease associations (Open Targets): platelet count, mean platelet volume and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 66 |
|---|---|
| UniProt accession | Q68CR7 |
| Gene | LRRC66 |
| Organism | Homo sapiens |
| Length | 880 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- platelet count · score 0.37
- mean platelet volume · score 0.30
- body height · score 0.26
- type 2 diabetes mellitus · score 0.25
- fat body mass · score 0.24
- lean body mass · score 0.23
- body weight · score 0.23
- body mass index · score 0.23
- platelet crit · score 0.22
- age at menopause · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q68CR7-F1 | alphafold | PREDICTED | 46.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q68CR7.
Amino-acid sequence (880 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC66?
The strongest Open Targets associations for LRRC66 are platelet count, mean platelet volume, body height, type 2 diabetes mellitus and fat body mass.
How long is the LRRC66 protein?
The Homo sapiens LRRC66 protein (UniProt Q68CR7) is 880 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q68CR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q68CR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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