Schlafen family member 13 (SLFN13)
Homo sapiens — UniProt Q68D06
Data last refreshed: (UniProt release unknown)
Key facts
Schlafen family member 13 (SLFN13) is a protein from Homo sapiens identified by UniProt accession Q68D06, 897 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q68D06; gene symbol SLFN13.
- Organism: Homo sapiens.
- Length: 897 amino acids.
- Top disease associations (Open Targets): leukocyte count, lymphocyte count and mean reticulocyte volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Schlafen family member 13 |
|---|---|
| UniProt accession | Q68D06 |
| Gene | SLFN13 |
| Organism | Homo sapiens |
| Length | 897 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.37
- lymphocyte count · score 0.27
- mean reticulocyte volume · score 0.26
- neutrophil count · score 0.24
- reticulocyte measurement · score 0.14
- reticulocyte count · score 0.14
- eosinophil count · score 0.10
- eosinophil percentage of leukocytes · score 0.10
- myeloid white cell count · score 0.08
- Immature Reticulocyte Fraction Measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q68D06-F1 | alphafold | PREDICTED | 87.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q68D06.
Amino-acid sequence (897 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLFN13?
The strongest Open Targets associations for SLFN13 are leukocyte count, lymphocyte count, mean reticulocyte volume, neutrophil count and reticulocyte measurement.
How long is the SLFN13 protein?
The Homo sapiens SLFN13 protein (UniProt Q68D06) is 897 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q68D06 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q68D06 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.