Cell division cycle-associated protein 2 (CDCA2)
Homo sapiens — UniProt Q69YH5
Data last refreshed: (UniProt release unknown)
Key facts
Cell division cycle-associated protein 2 (CDCA2) is a protein from Homo sapiens identified by UniProt accession Q69YH5, 1023 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.
- UniProt accession: Q69YH5; gene symbol CDCA2.
- Organism: Homo sapiens.
- Length: 1023 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, mean reticulocyte volume and BMI-adjusted waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cell division cycle-associated protein 2 |
|---|---|
| UniProt accession | Q69YH5 |
| Gene | CDCA2 |
| Organism | Homo sapiens |
| Length | 1023 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (110)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.35
- mean reticulocyte volume · score 0.33
- BMI-adjusted waist circumference · score 0.32
- triglyceride measurement · score 0.32
- waist-hip ratio · score 0.32
- Red cell distribution width · score 0.31
- high density lipoprotein cholesterol measurement · score 0.30
- uterine fibroid · score 0.26
- body height · score 0.24
- appendicular lean mass · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q69YH5-F1 | alphafold | PREDICTED | 46.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q69YH5.
Amino-acid sequence (1023 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDCA2?
The strongest Open Targets associations for CDCA2 are BMI-adjusted waist-hip ratio, mean reticulocyte volume, BMI-adjusted waist circumference, triglyceride measurement and waist-hip ratio.
How long is the CDCA2 protein?
The Homo sapiens CDCA2 protein (UniProt Q69YH5) is 1023 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q69YH5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q69YH5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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