Ankyrin repeat domain-containing protein 34A (ANKRD34A)
Homo sapiens — UniProt Q69YU3
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 34A (ANKRD34A) is a protein from Homo sapiens identified by UniProt accession Q69YU3, 496 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q69YU3; gene symbol ANKRD34A.
- Organism: Homo sapiens.
- Length: 496 amino acids.
- Top disease associations (Open Targets): neutrophil count, leukocyte count and neurogenic locus notch homolog protein 2 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 34A |
|---|---|
| UniProt accession | Q69YU3 |
| Gene | ANKRD34A |
| Organism | Homo sapiens |
| Length | 496 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.19
- leukocyte count · score 0.11
- neurogenic locus notch homolog protein 2 measurement · score 0.08
- glioblastoma multiforme · score 0.02
- medulloblastoma · score 0.02
- ependymoma · score 0.02
- atypical teratoid rhabdoid tumor · score 0.02
- astrocytoma · score 0.01
- oligodendroglioma · score 0.01
- Alzheimer disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q69YU3-F1 | alphafold | PREDICTED | 58.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q69YU3.
Amino-acid sequence (496 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD34A?
The strongest Open Targets associations for ANKRD34A are neutrophil count, leukocyte count, neurogenic locus notch homolog protein 2 measurement, glioblastoma multiforme and medulloblastoma.
How long is the ANKRD34A protein?
The Homo sapiens ANKRD34A protein (UniProt Q69YU3) is 496 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q69YU3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q69YU3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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