Zinc finger protein 660 (ZNF660)

About Zinc finger protein 660

Zinc finger protein 660 (ZNF660) is a protein from Homo sapiens identified by UniProt accession Q6AZW8, 331 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Zinc finger protein 660
UniProt accession	Q6AZW8
Gene	ZNF660
Organism	Homo sapiens
Length	331 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

functional brain measurement · score 0.10
pachyonychia congenita · score 0.07
urate measurement · score 0.06
unipolar depression · score 0.06
major depressive disorder · score 0.06
particulate matter air pollution measurement · score 0.05
depressive symptom measurement · score 0.03
cystatin C measurement · score 0.03
IGF-1 measurement · score 0.03
acanthosis nigricans · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6AZW8-F1	alphafold	PREDICTED	82.74	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6AZW8.

Amino-acid sequence (331 residues)

MRRKTRNFKH KTVKDNKVLT EGSDQESEKD NSQCCDPATN ERVQAEKRQY VCTECGKAFS QSANLTVHER IHTGEKPYKC KECGKAFSHS SNLVVHRRIH TGLKPYTCSE CGKSFSGKSH LIRHQGIHSG EKTYECKECG KAFSRSSGLI SHHRVHTGEK PYSCIECGKA FSRSSNLTQH QRMHRGKKVY KCKECGKTCG SNTKIMDHQR IHTGEKPYEC DECGKTFILR KTLNEHQRLH RREKPYKCNE CGKAFTSNRN LVDHQRVHTG EKPYKCNECG KTFRQTSQVI LHLRTHTKEK PYKCSECGKA YRYSSQLIQH QRKHNEEKET S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards