Scavenger receptor class A member 3 (SCARA3)
Homo sapiens — UniProt Q6AZY7
Data last refreshed: (UniProt release unknown)
Key facts
Scavenger receptor class A member 3 (SCARA3) is a protein from Homo sapiens identified by UniProt accession Q6AZY7, 606 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q6AZY7; gene symbol SCARA3.
- Organism: Homo sapiens.
- Length: 606 amino acids.
- Top disease associations (Open Targets): body height, adolescent idiopathic scoliosis and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Scavenger receptor class A member 3 |
|---|---|
| UniProt accession | Q6AZY7 |
| Gene | SCARA3 |
| Organism | Homo sapiens |
| Length | 606 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- body height · score 0.38
- adolescent idiopathic scoliosis · score 0.27
- Alzheimer disease · score 0.24
- smoking status measurement · score 0.09
- smoking initiation · score 0.08
- appendicular lean mass · score 0.08
- cannabis dependence · score 0.07
- smoking cessation · score 0.07
- schizophrenia · score 0.06
- chronic obstructive pulmonary disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6AZY7-F1 | alphafold | PREDICTED | 69.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6AZY7.
Amino-acid sequence (606 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCARA3?
The strongest Open Targets associations for SCARA3 are body height, adolescent idiopathic scoliosis, Alzheimer disease, smoking status measurement and smoking initiation.
How long is the SCARA3 protein?
The Homo sapiens SCARA3 protein (UniProt Q6AZY7) is 606 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6AZY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6AZY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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