Hemoglobin subunit mu (HBM)
Homo sapiens — UniProt Q6B0K9
Data last refreshed: (UniProt release unknown)
Key facts
Hemoglobin subunit mu (HBM) is a protein from Homo sapiens identified by UniProt accession Q6B0K9, 141 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q6B0K9; gene symbol HBM.
- Organism: Homo sapiens.
- Length: 141 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, reticulocyte measurement and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Hemoglobin subunit mu |
|---|---|
| UniProt accession | Q6B0K9 |
| Gene | HBM |
| Organism | Homo sapiens |
| Length | 141 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.63
- reticulocyte measurement · score 0.63
- reticulocyte count · score 0.63
- mean corpuscular hemoglobin · score 0.62
- erythrocyte count · score 0.52
- mean corpuscular hemoglobin concentration · score 0.46
- Alpha-thalassemia · score 0.42
- alpha thalassemia spectrum · score 0.42
- Red cell distribution width · score 0.38
- red blood cell density measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6B0K9-F1 | alphafold | PREDICTED | 95.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6B0K9.
Amino-acid sequence (141 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HBM?
The strongest Open Targets associations for HBM are mean corpuscular volume, reticulocyte measurement, reticulocyte count, mean corpuscular hemoglobin and erythrocyte count.
How long is the HBM protein?
The Homo sapiens HBM protein (UniProt Q6B0K9) is 141 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6B0K9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6B0K9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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