Insulin growth factor-like family member 4 (IGFL4)
Homo sapiens — UniProt Q6B9Z1
Data last refreshed: (UniProt release unknown)
Key facts
Insulin growth factor-like family member 4 (IGFL4) is a protein from Homo sapiens identified by UniProt accession Q6B9Z1, 124 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q6B9Z1; gene symbol IGFL4.
- Organism: Homo sapiens.
- Length: 124 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Insulin growth factor-like family member 4 |
|---|---|
| UniProt accession | Q6B9Z1 |
| Gene | IGFL4 |
| Organism | Homo sapiens |
| Length | 124 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- blood protein measurement · score 0.10
- PHF-tau measurement · score 0.10
- lipid measurement · score 0.10
- colorectal adenocarcinoma · score 0.05
- non-small cell lung carcinoma · score 0.04
- metabolite measurement · score 0.04
- colorectal cancer · score 0.03
- breast carcinoma · score 0.02
- COVID-19 · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6B9Z1-F1 | alphafold | PREDICTED | 69.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6B9Z1.
Amino-acid sequence (124 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGFL4?
The strongest Open Targets associations for IGFL4 are neurodegenerative disease, blood protein measurement, PHF-tau measurement, lipid measurement and colorectal adenocarcinoma.
How long is the IGFL4 protein?
The Homo sapiens IGFL4 protein (UniProt Q6B9Z1) is 124 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6B9Z1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6B9Z1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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