Fc receptor-like B (FCRLB)

About Fc receptor-like B

Fc receptor-like B (FCRLB) is a protein from Homo sapiens identified by UniProt accession Q6BAA4, 426 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

Target properties

Protein name	Fc receptor-like B
UniProt accession	Q6BAA4
Gene	FCRLB
Organism	Homo sapiens
Length	426 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (70)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.37
total blood protein measurement · score 0.33
serum non-albumin protein measurement · score 0.28
leukocyte count · score 0.28
aspartate aminotransferase measurement · score 0.25
alkaline phosphatase measurement · score 0.17
blood protein measurement · score 0.13
erythrocyte count · score 0.08
autosomal systemic lupus erythematosus type 16 · score 0.05
mean corpuscular hemoglobin concentration · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6BAA4-F1	alphafold	PREDICTED	74.55	—

Amino-acid sequence (426 residues)

MWPLTALLLL VPSSGQAATL EKPILSLHPP WTTIFKGERV TLKCDGYHPL LLELQPISTL WYLGHLLLPS HKKSIEVQTP GVYRCQTRGA PVSDPIHLSV SNDWLILQVP YAPVFEGEPL VLRCRGWYDK VVYKLHYYHD GQAVRYFHSS ANYTVLQARA SDSGRYQCSG TMRIPVESAP MFSAKVAVTV QELFRAPVLR VMGPREARGA ALGGVVLRCD TRLHPQKRDT PLQFAFYKYS RAVRRFDWGA EYTVPEPEVE ELESYWCEAA TATRSVRKRS PWLQLPGPGS PLDPASTTAP APWAAALAPG NRPLSFRKPP VSRSVPLVTS VRNTTSTGLQ FPASGAPTAG PPACAPPTPL EQSAGALKPD VDLLLREMQL LKGLLSRVVL ELKEPQALRE LRGTPETPTS HFAVSPGTPE TTPVES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards