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Fc receptor-like B (FCRLB)

Homo sapiens — UniProt Q6BAA4

Gene: FCRLBHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Fc receptor-like B (FCRLB) is a protein from Homo sapiens identified by UniProt accession Q6BAA4, 426 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

  • UniProt accession: Q6BAA4; gene symbol FCRLB.
  • Organism: Homo sapiens.
  • Length: 426 amino acids.
  • Top disease associations (Open Targets): lymphocyte count, total blood protein measurement and serum non-albumin protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFc receptor-like B
UniProt accessionQ6BAA4
GeneFCRLB
OrganismHomo sapiens
Length426 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (70)

Diseases linked to this target (Open Targets).

  • lymphocyte count · score 0.37
  • total blood protein measurement · score 0.33
  • serum non-albumin protein measurement · score 0.28
  • leukocyte count · score 0.28
  • aspartate aminotransferase measurement · score 0.25
  • alkaline phosphatase measurement · score 0.17
  • blood protein measurement · score 0.13
  • erythrocyte count · score 0.08
  • autosomal systemic lupus erythematosus type 16 · score 0.05
  • mean corpuscular hemoglobin concentration · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6BAA4-F1alphafoldPREDICTED74.55—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6BAA4.

Amino-acid sequence (426 residues)

MWPLTALLLL VPSSGQAATL EKPILSLHPP WTTIFKGERV TLKCDGYHPL LLELQPISTL WYLGHLLLPS HKKSIEVQTP GVYRCQTRGA PVSDPIHLSV SNDWLILQVP YAPVFEGEPL VLRCRGWYDK VVYKLHYYHD GQAVRYFHSS ANYTVLQARA SDSGRYQCSG TMRIPVESAP MFSAKVAVTV QELFRAPVLR VMGPREARGA ALGGVVLRCD TRLHPQKRDT PLQFAFYKYS RAVRRFDWGA EYTVPEPEVE ELESYWCEAA TATRSVRKRS PWLQLPGPGS PLDPASTTAP APWAAALAPG NRPLSFRKPP VSRSVPLVTS VRNTTSTGLQ FPASGAPTAG PPACAPPTPL EQSAGALKPD VDLLLREMQL LKGLLSRVVL ELKEPQALRE LRGTPETPTS HFAVSPGTPE TTPVES

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FCRLB?

The strongest Open Targets associations for FCRLB are lymphocyte count, total blood protein measurement, serum non-albumin protein measurement, leukocyte count and aspartate aminotransferase measurement.

How long is the FCRLB protein?

The Homo sapiens FCRLB protein (UniProt Q6BAA4) is 426 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6BAA4
GeneFCRLB
OrganismHomo sapiens
Length426
Binders0
Diseases70
View on UniProt