Rab15 effector protein (REP15)
Homo sapiens — UniProt Q6BDI9
Data last refreshed: (UniProt release unknown)
Key facts
Rab15 effector protein (REP15) is a protein from Homo sapiens identified by UniProt accession Q6BDI9, 236 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q6BDI9; gene symbol REP15.
- Organism: Homo sapiens.
- Length: 236 amino acids.
- Top disease associations (Open Targets): bone measurement, type 2 diabetes mellitus and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rab15 effector protein |
|---|---|
| UniProt accession | Q6BDI9 |
| Gene | REP15 |
| Organism | Homo sapiens |
| Length | 236 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- bone measurement · score 0.21
- type 2 diabetes mellitus · score 0.10
- bone density · score 0.10
- urate measurement · score 0.10
- cortical surface area measurement · score 0.09
- cortical thickness · score 0.07
- mitochondrial DNA measurement · score 0.06
- FEV/FVC ratio · score 0.06
- melorheostosis · score 0.05
- dacryocystitis-osteopoikilosis syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6BDI9-F1 | alphafold | PREDICTED | 80.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6BDI9.
Amino-acid sequence (236 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with REP15?
The strongest Open Targets associations for REP15 are bone measurement, type 2 diabetes mellitus, bone density, urate measurement and cortical surface area measurement.
How long is the REP15 protein?
The Homo sapiens REP15 protein (UniProt Q6BDI9) is 236 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6BDI9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6BDI9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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