Transcription factor Sp5 (SP5)
Homo sapiens — UniProt Q6BEB4
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor Sp5 (SP5) is a protein from Homo sapiens identified by UniProt accession Q6BEB4, 398 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q6BEB4; gene symbol SP5.
- Organism: Homo sapiens.
- Length: 398 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lobe attachment and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor Sp5 |
|---|---|
| UniProt accession | Q6BEB4 |
| Gene | SP5 |
| Organism | Homo sapiens |
| Length | 398 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- lobe attachment · score 0.36
- mathematical ability · score 0.29
- visceral adipose tissue measurement · score 0.28
- outer ear morphology trait · score 0.24
- PHF-tau measurement · score 0.23
- lobe size · score 0.23
- waist circumference · score 0.13
- BMI-adjusted waist-hip ratio · score 0.12
- hair shape measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6BEB4-F1 | alphafold | PREDICTED | 54.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6BEB4.
Amino-acid sequence (398 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SP5?
The strongest Open Targets associations for SP5 are neurodegenerative disease, lobe attachment, mathematical ability, visceral adipose tissue measurement and outer ear morphology trait.
How long is the SP5 protein?
The Homo sapiens SP5 protein (UniProt Q6BEB4) is 398 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6BEB4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6BEB4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.