Fatty-acid amide hydrolase 2 (FAAH2)
Homo sapiens — UniProt Q6GMR7
Data last refreshed: (UniProt release unknown)
Key facts
Fatty-acid amide hydrolase 2 (FAAH2) is a protein from Homo sapiens identified by UniProt accession Q6GMR7, 532 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q6GMR7; gene symbol FAAH2.
- Organism: Homo sapiens.
- Length: 532 amino acids.
- Top disease associations (Open Targets): mean platelet volume, Intellectual disability and Autistic behavior.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fatty-acid amide hydrolase 2 |
|---|---|
| UniProt accession | Q6GMR7 |
| Gene | FAAH2 |
| Organism | Homo sapiens |
| Length | 532 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.20
- Intellectual disability · score 0.11
- Autistic behavior · score 0.11
- head and neck squamous cell carcinoma · score 0.11
- androgenetic alopecia · score 0.05
- type 2 diabetes mellitus · score 0.03
- nonpapillary renal cell carcinoma · score 0.01
- psychiatric disorder · score 0.01
- Obesity · score 0.00
- COVID-19 · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6GMR7-F1 | alphafold | PREDICTED | 93.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6GMR7.
Amino-acid sequence (532 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAAH2?
The strongest Open Targets associations for FAAH2 are mean platelet volume, Intellectual disability, Autistic behavior, head and neck squamous cell carcinoma and androgenetic alopecia.
How long is the FAAH2 protein?
The Homo sapiens FAAH2 protein (UniProt Q6GMR7) is 532 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6GMR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6GMR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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