Putative peptidyl-tRNA hydrolase PTRHD1 (PTRHD1)
Homo sapiens — UniProt Q6GMV3
Data last refreshed: (UniProt release unknown)
Key facts
Putative peptidyl-tRNA hydrolase PTRHD1 (PTRHD1) is a protein from Homo sapiens identified by UniProt accession Q6GMV3, 140 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q6GMV3; gene symbol PTRHD1.
- Organism: Homo sapiens.
- Length: 140 amino acids.
- Top disease associations (Open Targets): Parkinson disease, parkinsonian disorder and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative peptidyl-tRNA hydrolase PTRHD1 |
|---|---|
| UniProt accession | Q6GMV3 |
| Gene | PTRHD1 |
| Organism | Homo sapiens |
| Length | 140 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.34
- parkinsonian disorder · score 0.34
- body height · score 0.23
- body fat percentage · score 0.19
- sitting height measurement · score 0.15
- testosterone measurement · score 0.14
- age at menarche · score 0.14
- multiple sclerosis · score 0.14
- appendicular lean mass · score 0.13
- intelligence · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6GMV3-F1 | alphafold | PREDICTED | 90.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6GMV3.
Amino-acid sequence (140 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PTRHD1?
The strongest Open Targets associations for PTRHD1 are Parkinson disease, parkinsonian disorder, body height, body fat percentage and sitting height measurement.
How long is the PTRHD1 protein?
The Homo sapiens PTRHD1 protein (UniProt Q6GMV3) is 140 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6GMV3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6GMV3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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