OTU domain-containing protein 7B (OTUD7B)
Homo sapiens — UniProt Q6GQQ9
Data last refreshed: (UniProt release unknown)
Key facts
OTU domain-containing protein 7B (OTUD7B) is a protein from Homo sapiens identified by UniProt accession Q6GQQ9, 843 residues long. MolForge cross-references it against 0 known binders and 198 disease associations.
- UniProt accession: Q6GQQ9; gene symbol OTUD7B.
- Organism: Homo sapiens.
- Length: 843 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, heel bone mineral density and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | OTU domain-containing protein 7B |
|---|---|
| UniProt accession | Q6GQQ9 |
| Gene | OTUD7B |
| Organism | Homo sapiens |
| Length | 843 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (198)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- heel bone mineral density · score 0.22
- head and neck squamous cell carcinoma · score 0.22
- body height · score 0.19
- BMI-adjusted waist circumference · score 0.19
- esophageal cancer · score 0.18
- lung adenocarcinoma · score 0.18
- gastric adenocarcinoma · score 0.18
- squamous cell lung carcinoma · score 0.18
- endometrial cancer · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6GQQ9-F1 | alphafold | PREDICTED | 66.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6GQQ9.
Amino-acid sequence (843 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTUD7B?
The strongest Open Targets associations for OTUD7B are breast adenocarcinoma, heel bone mineral density, head and neck squamous cell carcinoma, body height and BMI-adjusted waist circumference.
How long is the OTUD7B protein?
The Homo sapiens OTUD7B protein (UniProt Q6GQQ9) is 843 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6GQQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6GQQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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