N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (PM20D1)
Homo sapiens — UniProt Q6GTS8
Data last refreshed: (UniProt release unknown)
Key facts
N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (PM20D1) is a protein from Homo sapiens identified by UniProt accession Q6GTS8, 502 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q6GTS8; gene symbol PM20D1.
- Organism: Homo sapiens.
- Length: 502 amino acids.
- Top disease associations (Open Targets): interleukin-22 receptor subunit alpha-1 measurement, serum albumin measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-fatty-acyl-amino acid synthase/hydrolase PM20D1 |
|---|---|
| UniProt accession | Q6GTS8 |
| Gene | PM20D1 |
| Organism | Homo sapiens |
| Length | 502 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- interleukin-22 receptor subunit alpha-1 measurement · score 0.26
- serum albumin measurement · score 0.21
- monocyte count · score 0.18
- total blood protein measurement · score 0.16
- monocyte percentage of leukocytes · score 0.15
- reaction time measurement · score 0.14
- cortical thickness · score 0.14
- electrocardiography · score 0.14
- neuroimaging measurement · score 0.13
- brain measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6GTS8-F1 | alphafold | PREDICTED | 89.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6GTS8.
Amino-acid sequence (502 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PM20D1?
The strongest Open Targets associations for PM20D1 are interleukin-22 receptor subunit alpha-1 measurement, serum albumin measurement, monocyte count, total blood protein measurement and monocyte percentage of leukocytes.
How long is the PM20D1 protein?
The Homo sapiens PM20D1 protein (UniProt Q6GTS8) is 502 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6GTS8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6GTS8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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